Promethazine with codeine syrup is indicated for that short term reduction of coughs and higher respiratory signs and symptoms connected to allergy or maybe the typical chilly.

Antihistamines and codeine are both contraindicated to be used within the remedy of lessen respiratory tract signs and symptoms, which include asthma.

Promethazine hydrochloride happens for a white to faint yellow, almost odorless, crystalline powder which bit by bit oxidizes and turns blue on extended publicity to air.

The consequences of concomitant use or discontinuation of cytochrome P450 3A4 inducers, 3A4 inhibitors, or 2D6 inhibitors with codeine are elaborate.

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The combination of promethazine hydrochloride and codeine phosphate is contraindicated in pediatric individuals fewer than six decades of age. Concomitant administration of promethazine products and solutions with other respiratory depressants has an association with respiratory melancholy, and at times Dying, in pediatric people. The association does in a roundabout way relate to individualized weight-centered dosing, which might if not permit Safe and sound administration.

This medication may possibly interfere with certain lab checks (for instance urine pregnancy tests, skin allergy exams), maybe leading to Fake test outcomes. Make sure lab staff and your Medical doctors know you utilize this drug.

Codeine Within an embryofetal advancement research in Expecting rats dosed throughout the duration of organogenesis, codeine improved resorptions and lessened fetal weights at a dose roughly twenty five situations the MRHD (with a mg/m2 foundation having a maternal oral dose of one hundred twenty mg/kg/day); nonetheless, these consequences occurred while in the presence of maternal toxicity.

Browse the Medication Tutorial supplied by your pharmacist Before you begin getting codeine/promethazine and every time you can get a refill. When you have any concerns, inquire your physician or pharmacist.

If this SPL has inactivated NDCs listed via the FDA initiated compliance action, They are going to be specified as such.

Promethazine hydrochloride wasn't mutagenic while in the in vitro bacterial reverse mutation assay or clastogenic from the in vitro Chinese hamster ovary (CHO) mobile chromosomal aberration assay.

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When useful for an prolonged time, this medication may well not do the job likewise and could Promethazine codeine syrup involve unique dosing. Talk to your medical professional if this medication stops Operating nicely.

The quantity of medication that you simply get is determined by the power in the medication. Also, the volume of doses you're taking each day, the time allowed between doses, and the amount of time you take the drugs depend upon the clinical challenge for which you're utilizing the medicine.